Developments in Nanomaterials Applied to Biosensing
DOI:
https://doi.org/10.54691/ck6gzy23Keywords:
Nanomaterials, biosensing, disease diagnosis, environmental monitoring, research progress.Abstract
In recent years, the application and development of nanomaterials in the field of biosensors has become a hot topic in scientific research. With their unique physical and chemical properties, such as size effect, surface effect, and quantum effect, nanomaterials provide new research ideas and technical approaches for the development of biosensor technology. This paper systematically overviews the main types of nanomaterials and biosensors, and introduces in detail the preparation methods and key physical properties of various nanomaterials, including plasmonic nanomaterials, carbon-based nanomaterials, metal-organic frameworks, etc. On this basis, this paper focuses on summarizing the latest research progress of nanomaterials in the field of biosensors in recent years, specifically involving four key application directions: disease screening and diagnosis, drug residue detection, material performance optimization, and environmental monitoring. By systematically sorting out and looking forward to the cutting-edge applications of nanomaterials in the field of biosensors, it aims to provide valuable references for researchers in related fields and bring new inspiration to the basic research and application development of nanomaterials in the future.
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[1] Li, L., Wang, T., & Zhong, Y. (2024). A review of nanomaterials for biosensing applications. Journal of Materials Chemistry B, 12, 1168–1193.
[2] Zhang, R. (2023). Application and development prospects of nanomaterials in multiple fields. Applied and Computational Engineering, 23, 96–101.
[3] Xu, B., Xiang, X., Luo, Z., & Wang, D. (2023). Development of ultrasensitive new sensor based on functionalized triangular gold nanosheets layers for SARS-CoV-2 detection. IEEE Sensors Journal, 23(23), 28597–28604.
[4] Liu, Y., Zhang, J., Chen, X., Ren, L., et al. (2025). Integrated biomarker separation and detection with carbon nanotubes: Advances and prospects. Small Methods, 9(3), 9030119.
[5] Han, Y., Chen, Q., & Zhang, P. (2024). Research progress of carbon dots in the field of fluorescence detection. Chemical Reagents, 46(8), 1–9.
[6] Asif, I. M., Di Giulio, T., Gagliani, F., Malitesta, C., & Mazzotta, E. (2025). Advances in the direct nanoscale integration of molecularly imprinted polymers (MIPs) with transducers for the development of high-performance nanosensors. Biosensors, 15(8), 509.
[7] Garcia-Rodrigo, L., Tortolini, C., González-Cortés, A., et al. (2025). A simple MOF-based nanosensor for bisphenol A detection: In vitro application in supernatant of human endothelial cell models. Biosensors and Bioelectronics: X, 100666.
[8] Batten, M. R., Gutiérrez-Orgaz, J. A., Maturi, F. E., et al. (2025). Near-infrared activation of upconversion platforms for non-redox-dependent release of Pt(II). Journal of Inorganic Biochemistry, 271, 112982.
[9] Li, L., Lan, Z., Qiao, H., et al. (2025). Design of NanoBiT-Nanobody-based FGL1 biosensors for early assisted diagnosis of esophageal cancer. Biomaterials, 320, 123286.
[10] Schlexer, P., Andersen, A. B., Sebok, B., Chorkendorff, I., Schiøtz, J., & Hansen, T. W. (2019). Size-dependence of the melting temperature of individual Au nanoparticles. Particle & Particle Systems Characterization, 36, 1800480.
[11] Kurdyukov, D. A., Eurov, D. A., Stovpiaga, E. Y., Kirilenko, D. A., Tomkovich, M. V., Yagovkina, M. A., Rybin, M. V., & Golubev, V. G. (2025). Novel solid state of silica with ultra-high specific surface area. Materials Today, 88, 146–154.
[12] Liu, H. (2016). Research status of nano copper particles. Guangzhou Chemical Industry, 44(16), 37–38, 49.
[13] Shi, W., Gao, T., Zhang, L., Ma, Y., Liu, Z., & Zhang, B. (2019). Tailoring the surface structures of iron oxide nanorods to support Au nanoparticles for CO oxidation. Chinese Journal of Catalysis, 40(12), 1884–1894.
[14] Zhao, C., Liu, S., Dang, W., et al. (2025). Enzyme-activated biosensor assisted by enzymatic rolling circle amplification for sensitive detection of APE1 and imaging in vivo. Analytical Chemistry, 97(30), 16690–16697.
[15] Sedeeq, F. T., Nasiri, H., Abbasian, K., et al. (2025). Ultrasensitive detection of amlodipine using plasmonic optical fiber sensors enhanced with graphene oxide and chitosan nanocomposite. Scientific Reports, 15, 28662.
[16] Shellaiah, M., & Sun, K. W. (2023). Review on carbon dot-based fluorescent detection of biothiols. Biosensors, 13, 335.
[17] Bi, F., Zhang, X., & Liu, T. (2025). Selective catalysis-guided ethylene sensing in rhizosphere using nanogold-functionalized microprobe. Sensors and Actuators B: Chemical, 444, 138432.
[18] Shondo, J., Veziroglu, S., Tjardts, T., et al. (2022). Nanoscale synergetic effects on Ag–TiO2 hybrid substrate for photoinduced enhanced Raman spectroscopy (PIERS) with ultra-sensitivity and reusability (Small 50/2022). Small, 18, 2270271.
[19] Gao, M., Zhang, X., Li, S., et al. (2025). Boric acid-functionalized PANI-ABA/PA hydrogel-based flexible pH sensor for real-time sweat monitoring. Analytica Chimica Acta, 1362, 344188.
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