Detection Technique for Determination of Residual Solvents in the API Tacrolimus

Authors

  • Weiwei Wu
  • Yadan Mao
  • Zhong Chen
  • Dandan Wang

DOI:

https://doi.org/10.6911/WSRJ.202408_10(8).0003

Keywords:

Tacrolimus, Ethanol, Ethyl acetate, Butyl acetate, N-hexane, Cyclohexane, Toluene, Acetonitrile, Acetone, Residue, Organic solvent.

Abstract

To establish the detection technique for determination of the residual solvents ethanol, ethyl acetate, butyl acetate, N-hexane or cyclohexane, toluene, acetonitrile and acetone popularly used as the solvents for preparation of the active pharmaceutical ingredient (API) tacrolimus as reported, in order to control the quality of the API, to be in line with the requirement as stated in ICH Q3C.

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References

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Published

2024-07-24

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Section

Articles

How to Cite

Wu, Weiwei, Yadan Mao, Zhong Chen, and Dandan Wang. 2024. “Detection Technique for Determination of Residual Solvents in the API Tacrolimus”. World Scientific Research Journal 10 (8): 18-23. https://doi.org/10.6911/WSRJ.202408_10(8).0003.