Recent Advances in Ginsenoside-mediated Nano Drug Delivery Systems
DOI:
https://doi.org/10.6911/WSRJ.202412_10(12).0009Keywords:
Ginsenoside; Anti-tumor; Mechanism of action; Nano-drug delivery system.Abstract
Panax ginseng, a widely recognized medicinal plant with significant economic value, has been extensively used in traditional medicine worldwide for millennia. Both in vivo and in vitro studies have demonstrated that ginsenosides exert antitumor, anti-inflammatory, and cardioprotective effects through various mechanisms. However, their clinical applications are limited due to unfavorable physicochemical properties, including low solubility, poor stability, short half-life, and rapid elimination and degradation in vivo. Consequently, ginsenoside-based nano-delivery systems and preparation technologies have attracted significant attention from researchers. This review summarizes recent advances in the study of ginsenoside-related antitumor, anti-inflammatory, and cardioprotective effects, as well as various nano-delivery systems, aiming to provide theoretical guidance for comprehensive research on ginsenosides.
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