Preparation and Characterisation of Gradient Silver-modified ZIF-8 Nanoparticles and Their Antibacterial Properties

Wenjing Bai; Zhongyi Zhao

doi:10.6919/ICJE.202504_11(4).0037

Authors

Wenjing Bai
Zhongyi Zhao

DOI:

https://doi.org/10.6919/ICJE.202504_11(4).0037

Keywords:

ZIF-8; Antibacterial; Titanium Alloys.

Abstract

Titanium alloys are widely used in medical implants due to their excellent biocompatibility and corrosion resistance. However, their biological inertness makes bonding with natural bone ineffective and susceptible to bacterial infection. In order to improve its performance in implants, this study explores the application of gradient silver-modified ZIF-8 nanoparticles (Ag@ZIF-8 NPs) on the surface of titanium alloys through their preparation and characterisation. ZIF-8 was used as the base material and 1%, 5% and 10% silver-modified ZIF-8 NPs were obtained by doping with different concentrations of silver.It was shown that Ag@ZIF-8 NPs remained stable in the framework structure of ZIF-8, while silver doping significantly enhanced their antibacterial properties. The structures were analyzed in detail by scanning electron microscopy SEM, XRD and FT-IR, and their antimicrobial efficacy against Escherichia coli and Staphylococcus aureus was assessed by plate counting method.The results showed that the increase of silver concentration significantly improved the antimicrobial performance, especially for 10% Ag@ZIF-8 samples. This study provides a new idea for the development of surface-modified materials for titanium alloys, which has important application prospects, especially in the enhancement of antimicrobial properties of medical implants.

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