Investigation of the Morphology of PCL-Based Electrospun Nanofibers under Different Experimental Parameters

Jiaqi Jiang; Xiaohong Chen; Tianming Lu; Honglei Zhou

doi:10.6919/ICJE.202505_11(5).0034

Authors

Jiaqi Jiang
Xiaohong Chen
Tianming Lu
Honglei Zhou

DOI:

https://doi.org/10.6919/ICJE.202505_11(5).0034

Keywords:

Core-Shell Structure; Coaxial Electrospinning; Polycaprolactone; Nanoparticles.

Abstract

This research examines how changes in concentration, flow rate, and the inclusion of various additives impact the morphological characteristics of electrospun nanofibers derived from polycaprolactone (PCL). These factors play a critical role in determining fiber diameter, surface features, and overall quality. The study systematically assesses the effects of these variables on the size, shape, and consistency of the nanofibers. Findings reveal that fine-tuning these parameters allows for the tailored design of fiber properties to meet specific requirements. For example, adjustments in concentration significantly alter fiber formation and structural integrity, whereas flow rate is closely linked to the diameter and uniformity of the fibers. Incorporating certain additives further improves the functional performance of the nanofibers. The outcomes of this work contribute essential knowledge for refining the electrospinning process of PCL-based nanofibers, establishing both a theoretical framework and practical evidence for their use in biomedical applications, filtration technologies, and packaging solutions.

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